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Why we split midlife support into two formulas, what each contains, and how clearly we separate studied amounts from traditional use.
Midlife has a rhythm of its own, and the needs of noon are not the needs of midnight. That observation is the whole reason Day Tide™ and Night Tide™ exist as two bottles instead of one. Here is a closer look at how we built the pair, what each formula contains, and where we are careful to stay modest about what a supplement can do.
Why two formulas
Daytime support should not make you drowsy, and evening support should not keep you up. Putting everything into a single capsule would mean compromising both, so we split the jobs. Day Tide™ is a daytime capsule and Night Tide™ is a wind-down capsule, designed as a matched pair to be taken across a full 24 hours. They are the first formulas in the Tide Line, our women's wellness line, and they are designed for the years around midlife transition (the guide we use is ages 45 to 55, though ages are a guide and not a gate).
Every ingredient is included for a structure and function role: supporting the body's own systems through the midlife transition.* Menopause is a natural transition, and we do not frame it as a condition to be treated.
Inside Day Tide™
- ERr 731® Siberian rhubarb root (4 mg). A standardized extract of Rheum rhaponticum root, included at the amount used in published studies of the ingredient. It is a plant extract, not a hormone. We wrote a separate post on it.*
- Black cohosh and red clover. Traditional botanicals. Red clover is a source of plant isoflavones that support the transition.*
- Boswellia and curcumin. Boswellia is traditionally used to support joint comfort, and curcumin provides antioxidant curcuminoids.*
- Saffron. Supports a steady, positive mood.*
Inside Night Tide™
- Magnesium and L-theanine. Support a calm, relaxed state and restful, natural sleep.*
- Ashwagandha. Supports the body's healthy response to everyday stress.*
- Sage. A traditional botanical used to support comfort overnight.*
- Pycnogenol® (75 mg) and hyaluronic acid. Pycnogenol® is a French maritime pine bark extract that supports the body's normal antioxidant defenses and healthy circulation, and it sits within the 60 to 200 mg range used in published studies. Paired with hyaluronic acid, it supports skin and tissue hydration overnight.*
One clarification we like to make: Pycnogenol® is not in Night Tide™ as a sleep aid. The evening ingredients that support a calm wind-down are magnesium, L-theanine, ashwagandha and sage.*
A note on how much evidence sits behind each ingredient
Two ingredients, ERr 731® and Pycnogenol®, are included at amounts used in published studies of those ingredients. The doses of several of the other actives are below those used in clinical studies, and we include them in the traditional-use and compositional register. When we say "clinically studied," we mean the ingredient in published research, not the finished product. We think that distinction is worth stating out loud.
The marine thread: iodine-conscious by design
Both bottles are built on Everwild SeaMatrix™, our marine mineral complex led by Purple Sea Moss, so the same mineral foundation runs through morning and night. Many women keep an eye on iodine intake around midlife, and the words "sea moss" and "seaweed" can raise a flag for good reason: seaweed varies widely in iodine, and the content of many marine supplements is hard to know.
We formulate the complex to keep iodine low, we print the iodine amount in micrograms on the label, and finished batches are tested for iodine before release. Each Tide Line serving is designed to contain no more than 30 mcg of iodine, and the Night formula targets about 5 to 15 mcg. That is a transparency choice, not a treatment. If you have a thyroid condition or take thyroid medication, check with your provider before adding any new supplement.
Where the pair fits in the line
Who should check in first
These formulas are for adults 18 and over and are not for use during pregnancy or breastfeeding. Talk with your healthcare provider before starting if you take medication (including hormone therapy, hormonal birth control, blood thinners or thyroid medication), have a thyroid condition, have a history of hormone-sensitive conditions, have surgery scheduled, or are managing any medical condition. Day Tide™ and Night Tide™ contain black cohosh and ashwagandha. If you have a liver disorder, or notice unusual fatigue, abdominal pain, dark urine, or yellowing of the skin or eyes, stop use and contact your provider.
Formulas containing Wild Purple Sea Moss and bladderwrack provide naturally occurring iodine and are not recommended for those diagnosed with hyperthyroidism.
Sources
- Heger M, et al. Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomized, double-blind, placebo-controlled trial. Menopause. 2006;13(5):744-759. https://pubmed.ncbi.nlm.nih.gov/16894335/
- Weichmann F, Rohdewald P. Pycnogenol® French maritime pine bark extract in randomized, double-blind, placebo-controlled human clinical studies. Front Nutr. 2024;11:1389374. https://pubmed.ncbi.nlm.nih.gov/38757130/
- Chang JL, et al. Rheum rhaponticum extract (ERr 731): postmarketing data on safety surveillance and consumer complaints. Integr Med (Encinitas). 2016;15(3):34-39. https://pubmed.ncbi.nlm.nih.gov/27547165/
- National Center for Complementary and Integrative Health. Black Cohosh: Usefulness and Safety. https://www.nccih.nih.gov/health/black-cohosh
- National Center for Complementary and Integrative Health. Red Clover: Usefulness and Safety. https://www.nccih.nih.gov/health/red-clover
- National Center for Complementary and Integrative Health. Ashwagandha: Usefulness and Safety. https://www.nccih.nih.gov/health/ashwagandha
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Ashwagandha. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.ncbi.nlm.nih.gov/books/NBK548536/
- Linus Pauling Institute, Oregon State University. Curcumin. Micronutrient Information Center. https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/curcumin
- Yu G, et al. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020;20(1):225. https://pubmed.ncbi.nlm.nih.gov/32680575/
- Lopresti AL, et al. The effects of a saffron extract (affron®) on menopausal symptoms in women during perimenopause: a randomised, double-blind, placebo-controlled study. J Menopausal Med. 2021;27(2):66-78. https://pubmed.ncbi.nlm.nih.gov/34463070/
- European Medicines Agency. Salviae officinalis folium (sage leaf): herbal medicinal product. https://www.ema.europa.eu/en/medicines/herbal/salviae-officinalis-folium
- Hidese S, et al. Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: a randomized controlled trial. Nutrients. 2019;11(10):2362. https://pubmed.ncbi.nlm.nih.gov/31623400/
- Hsu TF, et al. Oral hyaluronan relieves wrinkles and improves dry skin: a 12-week double-blinded, placebo-controlled study. Nutrients. 2021;13(7):2220. https://pubmed.ncbi.nlm.nih.gov/34203487/
- Memorial Sloan Kettering Cancer Center. About Herbs: Pine Bark Extract. https://www.mskcc.org/cancer-care/integrative-medicine/herbs/pine-bark-extract
- NIH Office of Dietary Supplements. Magnesium: Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
- NIH Office of Dietary Supplements. Iodine: Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Iodine-HealthProfessional/
- Park SJ, et al. An update on the chemical constituents and biological properties of selected species of an underpinned genus of red algae: Chondrus. Mar Drugs. 2024;22(1):47. https://pubmed.ncbi.nlm.nih.gov/38248672/
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.