ZephyrCore for Practitioners: A Plain-Language Guide

This guide is for licensed practitioners and for readers who like to check the claims for themselves. It lays out what ZephyrCore contains, what each ingredient's evidence does and does not cover, and the language we use to describe it.

The design idea

ZephyrCore is built as a layer, not a standalone product. It contains no iodine and no plant material of its own, so it contributes an antioxidant layer that supports the body's normal antioxidant defenses alongside the rest of a regimen.* Practitioners often ask how it fits next to what a client already takes, and the short answer is that there is little to reconcile: no iodine to add up and no botanicals to overlap.

The formula

A serving is 2 capsules daily, from a bottle of 60 vegetarian capsules. Total actives are 671 mg per serving, with no proprietary blends.

• Setria® reduced L-glutathione, 250 mg. Fermentation-derived, pre-formed, in the active reduced state.
• Bio-Enhanced® Na-R-ALA, 221 mg. Stabilized sodium R-lipoate, at least 98% R-enantiomer, providing about 200 mg of R-lipoic acid.
• Eriomin® lemon flavonoid extract, 200 mg. Citrus limon, standardized to at least 70% eriocitrin.

It contains 0 mcg of iodine and is made in a GMP-certified facility, with third-party testing for purity, potency, and heavy metals.

What the evidence covers

Glutathione

Glutathione is described in the literature as the principal intracellular antioxidant and redox regulator. In a six-month randomized, double-blind, placebo-controlled trial of 54 healthy adults, 250 mg a day of oral glutathione raised glutathione by about 17% in blood and 29% in red blood cells. A 1,000 mg dose raised levels further, and the increases were dose and time dependent. After a one-month break, levels returned to baseline. This supports our language that Setria® at 250 mg helps raise the body's glutathione stores and supports natural antioxidant defenses and natural detoxification processes.*

R-lipoic acid

The R-enantiomer is the form the body makes. It works in both the water- and fat-based parts of the cell. In laboratory research, its reduced form helps return oxidized vitamin C, glutathione, and CoQ10 to their active forms, and vitamin E benefits through the network.* A human pharmacokinetic study found higher blood levels from the sodium R-lipoate form than from free R-lipoic acid.

Eriomin®

A 12-week, randomized, double-blind, placebo-controlled trial of 103 adults at 200, 400, and 800 mg measured total antioxidant capacity (about 6% higher) and lipid peroxidation (about 17% lower), along with inflammatory-response markers. A later crossover trial at 200 mg corroborated the inflammatory findings. This is the basis for describing Eriomin® as providing antioxidant support and helping support a healthy inflammatory response.*

Limits to keep in view

• The finished ZephyrCore formula has not been clinically tested. "Clinically studied" applies to the branded ingredients at the doses studied.
• The Eriomin® trials enrolled adults with blood sugar above the normal range and used glucose as the primary endpoint. They support the ingredient's antioxidant and inflammatory-response activity. They do not substantiate a blood sugar or respiratory benefit of the finished product, and we do not claim one.
• Lipoic acid recycling data come largely from laboratory studies. How fully this occurs in the body is still being studied.
• We do not claim ZephyrCore changes the absorption or activity of other supplements.

Language we use, and why

We keep claims to structure and function. These statements are the ceiling for how we describe the product.

• "An iodine-free antioxidant booster that layers over any routine."
• "Supplies the body's master antioxidant, then helps regenerate it."*
• "Supports the body's natural antioxidant defenses and its natural detoxification processes."*
• "Three branded, clinically studied ingredients at fully disclosed doses." This ties the study language to the ingredients, not to finished-product outcomes.

Fitting it into a client's routine

• With vitamin C, vitamin E, or CoQ10, the roles are complementary, with no overlap.
• With NAC or other glutathione-support products, the routes differ and the goal is shared.
• With curcumin and other polyphenols, Eriomin® is a different flavonoid family.
• With sea moss or marine minerals, ZephyrCore adds no iodine, so the total stays where it was.
• With another lipoic acid or glutathione product, review the doses together, because a client may not need both.

Cautions

ZephyrCore is for adults 18 and older and is not for use during pregnancy or breastfeeding. Alpha-lipoic acid and lemon flavonoids may affect blood sugar, so clients on blood sugar or diabetes medication should monitor closely and consult a provider first. Clients taking any medication, including blood thinners, blood pressure medication, or thyroid medication, or who have a medical condition or are scheduled for surgery, should consult a healthcare provider before use. This material is professional education and not a substitute for the judgment of a qualified practitioner.

Sources

1. Richie JP Jr, et al. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. 2015;54(2):251-263. https://pubmed.ncbi.nlm.nih.gov/24791752/
2. Packer L, et al. Alpha-lipoic acid as a biological antioxidant. Free Radic Biol Med. 1995;19(2):227-250. https://pubmed.ncbi.nlm.nih.gov/7649494/
3. Carlson DA, et al. The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects. Altern Med Rev. 2007;12(4):343-351. https://pubmed.ncbi.nlm.nih.gov/18069903/
4. Ribeiro CB, et al. Effectiveness of Eriomin® in managing hyperglycemia and reversal of prediabetes condition: a double-blind, randomized, controlled study. Phytother Res. 2019;33(7):1921-1933. https://pubmed.ncbi.nlm.nih.gov/31183921/
5. Cesar TB, et al. Nutraceutical eriocitrin (Eriomin) reduces hyperglycemia by increasing glucagon-like peptide 1 and downregulates systemic inflammation: a crossover-randomized clinical trial. J Med Food. 2022;25(11):1050-1058. https://pubmed.ncbi.nlm.nih.gov/35796695/
6. Lushchak VI. Glutathione homeostasis and functions: potential targets for medical interventions. J Amino Acids. 2012;2012:736837. https://pubmed.ncbi.nlm.nih.gov/22500213/
7. Superti F, Russo R. Alpha-lipoic acid: biological mechanisms and health benefits. Antioxidants (Basel). 2024;13(10):1228. https://pubmed.ncbi.nlm.nih.gov/39456481/
8. Yao L, et al. Eriocitrin: a review of pharmacological effects. Biomed Pharmacother. 2022;154:113563. https://pubmed.ncbi.nlm.nih.gov/35987162/
9. Linus Pauling Institute, Oregon State University. Lipoic Acid. Micronutrient Information Center. https://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.